Benzoyl chloride → N-(8-bromo[1,2,4]triazolo[1,5-a]pyridin-2-yl)benzamide

Participants

Reaction Steps

The title compound was prepared following procedure described for intermediate B1, but starting from 8-bromo[1,2,4]triazolo[1,5-a]pyridin-2-amine ((A15), 4.40 g; 20.7 mmol; 1.0 eq.) and benzoyl chloride (5.81 g; 41.3 mmol; 2.0 eq.) as a white solid (4.9 g, 74%). HPLC, Rt: 2.45 min. (purity 90.1%). LC/MS, M+(ESI): 318.9, M−(ESI): 316.9.

Provenance & Evidence