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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2382837Generated: October 25, 2026

4-Butylbenzoic acid → 4-butyl-N-[5-(3-furyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]benzamide

https://huagongshe.com/reaction/2382837

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Butylbenzoic acidHCID 88631—
Reactant5-(Furan-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amineHCID 25215938—
Product4-butyl-N-[5-(3-furyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]benzamideHCID 25213977—

Reaction Steps

The title compound was prepared following procedure and work up described for example 2, but starting from 5-(3-furyl)[1,2,4]triazolo[1,5-a]pyridin-2-amine ((A2), 75 mg; 0.37 mmol; 1.0 eq.) and 4-butylbenzoic acid (80 mg; 0.45 mmol; 1.2 eq.) as a yellow foam (20 mg, 15%). HPLC, Rt: 4.45 min. (purity 82.6%). LC/MS, M+(ESI): 361.1, M−(ESI): 359.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263595B2
Source datasetuspto-grants-2012_09
ORD IDord-89aa92c447cf425aaa9a9cf734ea9a19
Source noteuspto-grants-2012_09