2-Methoxyethylamine → HCID 25213978, compound

HRID 2382838Notes

Reaction equation

HRID 2382838 reaction equation
Cl[C:2]1[N:7]2[N:8]=[C:9]([NH:11][C:12](=[O:19])[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[N:10]=[C:6]2[CH:5]=[CH:4][CH:3]=1.[CH3:20][O:21][CH2:22][CH2:23][NH2:24]>>[CH3:20][O:21][CH2:22][CH2:23][NH:24][C:2]1[N:7]2[N:8]=[C:9]([NH:11][C:12](=[O:19])[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[N:10]=[C:6]2[CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 80182-MethoxyethylamineHCID 25212515HCID 25212515, compound

Product 1

HCID 25213978HCID 25213978, compound

Procedure

The title compound was prepared following procedure described for example 30 but starting from N-(5-chloro[1,2,4]triazolo[1,5-a]pyridin-2-yl)benzamide ((B3), 50 mg; 0.18 mmol; 1.0 eq.) and 2-methoxyethylamine (1.0 mL) as an off-white solid (52 mg, 91%). HPLC, Rt: 2.08 min. (purity 90.1%). LC/MS, M+(ESI): 312.1, M−(ESI): 310.1.

Sources & evidence

ORD record
ord-805cae1f466e4a3398a5b78b76588136
Source dataset
uspto-grants-2012_09
Patent number
US08263595B2

Reaction notes

Loading…