HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclooctylamine → N-[5-(cyclooctylamino)[1,2,4]triazolo[1,5-a]pyridin-2-yl]nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclooctylamine | HCID 2903 | — |
| Reactant | N-(5-chloro[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide | HCID 25212516 | — |
| Product | N-[5-(cyclooctylamino)[1,2,4]triazolo[1,5-a]pyridin-2-yl]nicotinamide | HCID 25214209 | — |
Reaction Steps
The title compound was prepared following procedure described for example 30 but starting from N-(5-chloro[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide ((B4), 58 mg; 0.21 mmol; 1.0 eq.) and cyclooctylamine (440 μL) as a white powder (4 mg, 4%). HPLC, Rt: 3.25 min. (purity 97.9%). LC/MS, M+(ESI): 365.4, M−(ESI): 363.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263595B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-112d64c07966418898f56453600f9170 |
| Source note | uspto-grants-2012_09 |