HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinecarbonyl chloride, hydrochloride (1:1) → HCID 59437452, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinecarbonyl chloride, hydrochloride (1:1) | HCID 88438 | — |
| Reactant | HCID 25216191 | HCID 25216191 | — |
| Product | HCID 59437452 | HCID 59437452 | — |
Reaction Steps
The title compound was prepared following procedure described for intermediate B1, but starting from 6-bromo-N5-cyclohexyl[1,2,4]triazolo[1,5-a]pyridine-2,5-diamine ((A14), 616 mg; 1.99 mmol; 1.0 eq.) and nicotinoyl chloride hydrochloride (424 mg; 2.38 mmol; 1.2 eq.) as a beige powder (99 mg, 12%). HPLC, Rt: 3.41 min. (purity 94.6%). LC/MS, M+(ESI): 416.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263595B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-ba4df26f745a40b6acd8b5a264d5d30a |
| Source note | uspto-grants-2012_09 |