HuagongsheHuagongshe Chemistry Print Report · For research reference only
N5-cyclohexyl[1,2,4]triazolo[1,5-a]pyridine-2,5-diamine → HCID 59437504, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N5-cyclohexyl[1,2,4]triazolo[1,5-a]pyridine-2,5-diamine | HCID 25216186 | — |
| Reactant | HCID 86643868 | HCID 86643868 | — |
| Product | HCID 59437504 | HCID 59437504 | — |
Reaction Steps
The title compound was prepared following procedure described for intermediate B1 but starting from N5-cyclohexyl[1,2,4]triazolo[1,5-a]pyridine-2,5-diamine ((A9), 116 mg; 0.5 mmol; 1.0 eq.) and 6-(2-pyrrolidin-1-ylethyl)nicotinoyl chloride (239 mg, 1.0 mmol; 2.0 eq.) as a white powder (130 mg, 60%). HPLC, Rt: 2.67 min. (purity 99.9%). LC/MS, M+(ESI): 434.1, M−(ESI): 432.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263595B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-6b6641101e604bd3a17a31e40750de89 |
| Source note | uspto-grants-2012_09 |