HuagongsheHuagongshe Chemistry Print Report · For research reference only
Succinimide → 1-{3-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]prop-2-en-1-yl}pyrrolidine-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Succinimide | HCID 11439 | — |
| Reactant | 2-(3-Chloroprop-1-en-1-yl)-4-(4-fluorophenyl)-1,3-thiazole | HCID 68821706 | — |
| Product | 1-{3-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]prop-2-en-1-yl}pyrrolidine-2,5-dione | HCID 68826244 | — |
Reaction Steps
The compound was prepared analogously to example 3e) from 100 mg (0.39 mmol) of 2-(3-chloropropenyl)-4-(4-fluorophenyl)thiazole and 46.8 mg (0.47 mmol) of pyrrolidine-2,5-dione. Yield: 24 mg (17%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642620B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-7b7c7ac22a5f4f13ad272c3f3ecd7a5f |
| Source note | uspto-grants-2014_02 |