Sodium borohydride → HCID 67538376, compound

Participants

Reaction Steps

1-cyclohexyl-N-isobutyl-3,4-dihydroisoquinoline-7-carboxamide (689 mg) was dissolved in MeOH (12 mL). Sodium borohydride (100 mg) was added to the reaction mixture, followed by stirring at room temperature for 5 hours. The solvent was evaporated. To the resulting residue were added water and chloroform. The residue was extracted with chloroform and dried over magnesium sulfate. Then, the solvent was evaporated under reduced pressure to obtain 1-cyclohexyl-N-isobutyl-1,2,3,4-tetrahydroisoquinoline-7-carboxamide.

Provenance & Evidence