Lithium hydroxide, monohydrate → HCID 45381833, compound

Participants

Reaction Steps

To a mixed solution of 2-(4-cyanonaphthalene-2-yl)-4-methyloxazole-5-carboxylic acid methyl ester (0.045 g) in tetrahydrofuran (1.5 mL), ethanol (0.8 mL) and water (0.8 mL) was added lithium hydroxide monohydrate (0.02 g), and the mixture was stirred for 30 minutes. To the reaction solution was added water, and the resulting mixture was washed with diethyl ether. To the aqueous layer was added 1 mol/L hydrochloric acid (0.5 mL). The precipitated solid was collected by filtration, and dried under reduced pressure to give the title compound (0.028 g).

Provenance & Evidence