HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-[4-[6-(4-aminophenoxy)-1-methyl-1H-benzimidazol-2-ylmethoxy]benzyl]thiazolidine-2,4-dione dihydrochloride → HCID 10186152, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-[4-[6-(4-aminophenoxy)-1-methyl-1H-benzimidazol-2-ylmethoxy]benzyl]thiazolidine-2,4-dione dihydrochloride | HCID 86587768 | — |
| Reactant | HCID 87673801 | HCID 87673801 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 10186152 | HCID 10186152 | — |
Reaction Steps
5-(4-(6-(4-Amino-phenoxy)-1-methyl-1H-benzimidazol-2-ylmethoxy)-benzyl)-thiazolidine-2,4-dione.dihydrochloride (Japanese Patent Application (Kokai) No. Hei 11-193276) was used in place of 5-(4-(6-(3-isopropylamino-phenoxy)-1-methyl-1H-benzimidazol-2-ylmethoxy)-benzyl)-thiazolidine-2,4-dione.dihydrochloride of Production Example 4, and acetone was used in place of acetaldehyde to give the title compound in similar manner to Production Example 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263631B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-e76a5a09d71b498fb838efa43e86f097 |
| Source note | uspto-grants-2012_09 |