HCID 86684861, compound → HCID 86684860, compound

HRID 238357Notes

Reaction equation

HRID 238357 reaction equation
[C:1]1([C:6]2[CH:11]=[CH:10][C:9]([C:12]3[N:16]([CH3:17])[N:15]=[CH:14][CH:13]=3)=[CH:8][CH:7]=2)[CH2:5][CH2:4][CH2:3][CH:2]=1>[C].[Pd].C(O)C>[CH:1]1([C:6]2[CH:11]=[CH:10][C:9]([C:12]3[N:16]([CH3:17])[N:15]=[CH:14][CH:13]=3)=[CH:8][CH:7]=2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

4

Reactant 1

HCID 86684861HCID 86684861, compound

Product 1

HCID 86684860HCID 86684860, compoundYield 104.3%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

10% palladium carbon (20 mg) was added to an ethanol (2.4 mL) solution of 5-[4-(cyclopenta-1-ene-1-yl)phenyl]-1-methyl-1H-pyrazole (133 mg), and the obtained solution was then stirred under a hydrogen atmosphere at a room temperature overnight. Thereafter, the reaction solution was filtrated with Celite, and the filtrate was then concentrated under a reduced pressure, so as to obtain the title compound (140 mg) in the form of a light yellow oily substance.

Workup

  1. filtrationThereafter, the reaction solution was filtrated with Celite
  2. concentrationthe filtrate was then concentrated under a reduced pressure

Sources & evidence

ORD record
ord-c4ea02a7f6f640d98431336921bedb3d
Source dataset
uspto-grants-2014_02
Patent number
US08642626B2

Reaction notes

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