Hydroquinone → HCID 68784217, compound

HRID 2383918Notes

Reaction equation

HRID 2383918 reaction equation
[S:1]1[C:5]2[CH:6]=[C:7]([NH2:10])[CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH3:11][C:12](=[CH:16][CH3:17])[C:13]([OH:15])=[O:14].C1(O)C=CC(O)=CC=1>C1(C)C=CC=CC=1>[S:1]1[C:5]2[CH:6]=[C:7]([NH:10][CH:16]([CH3:17])[CH:12]([CH3:11])[C:13]([OH:15])=[O:14])[CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

5

Reactant 3

HCID 785HydroquinoneHCID 66562-Butenoic acid, 2-methyl-HCID 682886-Aminobenzothiazole

Product 1

HCID 68784217HCID 68784217, compoundYield 6.02%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Benzothiazol-6-ylamine (1 g, 6.667 mmol) was reacted with 2-methyl-but-2-enoic acid (1 g, 9.99 mmol), benzene-1,4-diol (51.38 mg, 0.467 mmol) and toluene (6 mL) to afford the crude product. Purification by column chromatography on silica gel (50% ethyl acetate in hexane) afforded 100 mg of the product (6.02% yield).

Workup

  1. customto afford the crude product
  2. customPurification by column chromatography on silica gel (50% ethyl acetate in hexane)

Sources & evidence

ORD record
ord-f52898c291824d43906be3dc4765370a
Source dataset
uspto-grants-2012_09
Patent number
US08263635B2

Reaction notes

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