Hydrogen chloride-ethyl acetate → HCID 86684890, compound

Participants

Reaction Steps

To an ethyl acetate (0.76 mL) solution of the N-[2-(dimethylamino)ethyl]-3-({1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl}ethynyl)benzenesulfonamide (76 mg) obtained in Example 1, a 4 M HCl/ethyl acetate solution (48 μL) was added at a room temperature, and the obtained solution was then stirred for 3 hours. Thereafter, the generated solid was collected by filtration, and was then washed with ethyl acetate, so as to obtain the title compound (58 mg) in the form of a colorless solid.

Provenance & Evidence