HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-4-nitrophenol → Phenol, 4-amino-2-fluoro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-4-nitrophenol | HCID 9825 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Phenol, 4-amino-2-fluoro- | HCID 2735918 | 86% |
Reaction Steps
Under H2, a mixture of 2-fluoro-4-nitrophenol (10 g, 63.7 mmol) and Pd/C (1 g) in methanol (100 mL) was stirred at room temperature for 5 hours. The mixture was filtered, and concentrated in vacuo to give the compound 2A-1 (7 g, yield 86%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642628B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-38611150c2d34da9bd33717983526c26 |
| Source note | uspto-grants-2014_02 |