Methyl Thioglycolate → HCID 57883572, compound

HRID 2384154Notes

Reaction equation

Br[C:2]1[S:6][C:5]([NH:7][C:8](=[O:23])[N:9]([CH:16]2[CH2:21][CH2:20][CH:19]([CH3:22])[CH2:18][CH2:17]2)[CH:10]2[CH2:15][CH2:14][O:13][CH2:12][CH2:11]2)=[N:4][CH:3]=1.[C:24]([O:28][CH3:29])(=[O:27])[CH2:25][SH:26]>>[CH3:29][O:28][C:24](=[O:27])[CH2:25][S:26][C:2]1[S:6][C:5]([NH:7][C:8]([N:9]([CH:16]2[CH2:21][CH2:20][CH:19]([CH3:22])[CH2:18][CH2:17]2)[CH:10]2[CH2:15][CH2:14][O:13][CH2:12][CH2:11]2)=[O:23])=[N:4][CH:3]=1

Participants

Reactant 2

HCID 16907Methyl Thioglycolate

HCID 57883890HCID 57883890, compound

Product 1

HCID 57883572HCID 57883572, compound

Procedure

Prepared as described in general procedure (D) using 3-(5-bromo-thiazol-2-yl)-1-(4-methyl-cyclohexyl)-1-(tetrahydro-pyran-4-yl)-urea (Example 203) and methyl thioglycolate.

Workup

customPrepared

Sources & evidence

ORD record: ord-7be4a81cc3ff4037a8233c2b94ff4fec
Source dataset: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08263634B2

Reaction notes

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