3,5-Dichloroaniline → N-(3,5-Dichlorophenyl)-2-hydroxy-5-methoxybenzamide

HRID 2384441Notes

Reaction equation

HRID 2384441 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[C:7]([C:8]([OH:10])=O)[C:6]([OH:12])=[CH:5][CH:4]=1.[Cl:13][C:14]1[CH:15]=[C:16]([CH:18]=[C:19]([Cl:21])[CH:20]=1)[NH2:17]>>[Cl:13][C:14]1[CH:15]=[C:16]([NH:17][C:8](=[O:10])[C:7]2[CH:11]=[C:3]([O:2][CH3:1])[CH:4]=[CH:5][C:6]=2[OH:12])[CH:18]=[C:19]([Cl:21])[CH:20]=1

Participants

3

Reactant 2

HCID 122813,5-DichloroanilineHCID 757875-Methoxysalicylic Acid

Product 1

HCID 17860316N-(3,5-Dichlorophenyl)-2-hydroxy-5-methoxybenzamideYield 29.8%

Procedure

Using 5-methoxysalicylic acid and 3,5-dichloroaniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-fd63e2d6cacf45f6b9ba7d26f8dfcb0f
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Reaction notes

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