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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 238448Generated: October 25, 2026

1-(2-Chloroethyl)pyrrolidine → 1-[2-(5-Nitro-2-trifluoromethylphenoxy)ethyl]-pyrrolidine

https://huagongshe.com/reaction/238448

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Chloroethyl)pyrrolidineHCID 81669—
Reactant1-[2-(2-Tert-butyl-5-nitro-phenoxy)-ethyl]-piperidineHCID 21959506—
Reactant5-Nitro-2-(trifluoromethyl)phenolHCID 21959586—
Product1-[2-(5-Nitro-2-trifluoromethylphenoxy)ethyl]-pyrrolidineHCID 21959494—

Reaction Steps

1-[2-(5-Nitro-2-trifluoromethylphenoxy)ethyl]-pyrrolidine was prepared from 5-nitro-2-trifluoromethyl-phenol and 1-(2-chloroethyl)pyrrolidine by a procedure similar to that described for 1-[2-(2-tert-butyl-5-nitro-phenoxy)-ethyl]-piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08642624B2
Source datasetuspto-grants-2014_02
ORD IDord-00375ee15b7f4b8b87c66ddaf41cccb2
Source noteuspto-grants-2014_02