Hydrochloric Acid → HCID 178481021, compound

Participants

Reaction Conditions

Reaction Steps

82 g platinum on charcoal (5%) are added to a solution of 822 g (trans)-1-hydroxy-4-{[N-(2,2-dimethoxy-ethyl)-N-methyl-amino]-carbonylmethylamino}-cyclohexane in 4500 ml of methanol and 450 ml of water. After the addition of 499 ml concentrated hydrochloric acid hydrogenation with hydrogen is begun immediately. During the hydrogenation process the mixture is heated to 50° C. After 3 h it is filtered.

Provenance & Evidence