HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azobisisobutyronitrile → 2-Bromomethyl-4-nitro-1-pentafluoroethyl-benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 1-Pentafluoroethyl-2-methyl-4-nitro-benzene | HCID 10587102 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Bromomethyl-4-nitro-1-pentafluoroethyl-benzene | HCID 21959367 | — |
Reaction Steps
2-Methyl-4-nitro-1-pentafluoroethyl-benzene (2.55 g) was dissolved in CCl4 (30 ml) and AIBN (164 mg) and NBS (1.96 g) were added. The reaction was heated to reflux and stirred for 24 h. The mix was diluted with CH2Cl2, washed with sat'd NaHCO2, dried over MgSO4 and concentrated to give the compound as an oil which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642624B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-de09dcfcf01c43daa253618bd250f2a1 |
| Source note | uspto-grants-2014_02 |