Hydrochloric Acid → HCID 24803422, compound

HRID 2384910Notes

Reaction equation

HRID 2384910 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:33][C:11]3[C:12](=[O:32])[N:13]([C:16]4[CH:21]=[CH:20][C:19]([O:22][C@@H:23]5[CH2:28][CH2:27][CH2:26][N:25]([CH3:29])[CH2:24]5)=[C:18]([O:30][CH3:31])[CH:17]=4)[CH:14]=[CH:15][C:10]=3[CH:9]=2)=[CH:4][CH:3]=1.Cl>C(Cl)Cl.C(O)C>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:33][C:11]3[C:12](=[O:32])[N:13]([C:16]4[CH:21]=[CH:20][C:19]([O:22][C@@H:23]5[CH2:28][CH2:27][CH2:26][N:25]([CH3:29])[CH2:24]5)=[C:18]([O:30][CH3:31])[CH:17]=4)[CH:14]=[CH:15][C:10]=3[CH:9]=2)=[CH:4][CH:3]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 24803423HCID 24803423, compound

Product 1

HCID 24803422HCID 24803422, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 6344DichloromethaneSolvent

Procedure

Prepare the HCl salt by dissolving the residue in CH2Cl2 and adding HCl in ethanol. Add ether to the mixture then filter and dry the solid to obtain the title compound. LC-MS/ES m/z (35Cl) 481.0 [M+H]+.

Workup

  1. filtrationAdd ether to the mixture then filter
  2. customdry the solid

Sources & evidence

ORD record
ord-0d36d5d1b4f34819b40439dc3f29b0de
Source dataset
uspto-grants-2012_09
Patent number
US08263772B2

Reaction notes

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