反应详情

2-Fluoropyridine-3-carboxylic acid (7 g, Step C) was suspended in SOCl2 (100 mL). After heating under reflux for 2 h, the mixture became homogeneous. Excess SOCl2 was removed in vacuo to afford a brown solid as desired product.

1. temperatureAfter heating
2. temperatureunder reflux for 2 h
3. customExcess SOCl2 was removed in vacuo