反应详情

2-Ethylhexyl 2-cyano-3,3-diphenylacrylate (Eusolex® OCR; Merck) is dissolved in tetrahydrofuran (THF), and 5% Pd/C (56% water; Merck: Art. No. 275175) is added. The hydrogenation is subsequently carried out with hydrogen 3.0 at room temperature and atmospheric pressure. The catalyst is separated off by filtration. The filtrate is freed from solvent in vacuo, and the residue is washed. The organic phase is dried over sodium sulfate, and the solvent is removed in vacuo. The purification is carried out by filtration through silica gel, giving analytically pure product.

1. addition275175) is added
2. customat room temperature
3. customThe catalyst is separated off by filtration
4. washthe residue is washed
5. dry with materialThe organic phase is dried over sodium sulfate
6. customthe solvent is removed in vacuo
7. customThe purification
8. filtrationis carried out by filtration through silica gel
9. customgiving analytically pure product