反应详情

To a solution of (4-benzyloxy-6-fluoro-1-methyl-naphthalen-2-yl)-acetic acid methyl ester (50 mg) in methanol was added 10% palladium on carbon (10 mg). After being stirred at room temperature under a hydrogen atmosphere overnight, the resulting mixture was filtered. The filtrate was concentrated in vacuo to afford (6-fluoro-4-hydroxy-1-methyl-naphthalen-2-yl)-acetic acid methyl ester (30 mg) as a white solid.

1. filtrationthe resulting mixture was filtered
2. concentrationThe filtrate was concentrated in vacuo