HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonyl chloride → (3-{[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-methanesulfonyl-amino}-propyl)-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | {3-[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-propyl}-carbamic acid tert-butyl ester | HCID 86603243 | — |
| Product | (3-{[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-methanesulfonyl-amino}-propyl)-carbamic acid tert-butyl ester | HCID 86603242 | — |
Reaction Steps
Intermediate 2 from above was treated with methanesulfonyl chloride following procedure D. LC-MS showed the product had the expected M+H+ of 456.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268822B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-e82a31e58c8440abbe1f0de6fc321f26 |
| Source note | uspto-grants-2012_09 |