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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2386368Generated: October 25, 2026

2-(Pyridin-3-yl)ethan-1-amine → N-(3-(2-chloropyrimidin-4-yl)benzyl)-2-(pyridine-3-yl)ethanamine

https://huagongshe.com/reaction/2386368

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Pyridin-3-yl)ethan-1-amineHCID 854051—
Reactant3-(2-Chloro-pyrimidin-4-yl)-benzaldehydeHCID 24901965—
ProductN-(3-(2-chloropyrimidin-4-yl)benzyl)-2-(pyridine-3-yl)ethanamineHCID 86603256—

Reaction Steps

Intermediate 1 was coupled with 2-pyridin-3-yl-ethylamine following procedure B. LC-MS showed the product had the expected M+H+ of 325.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268822B2
Source datasetuspto-grants-2012_09
ORD IDord-0a4fa57ee4f647a4bb16ae531006009d
Source noteuspto-grants-2012_09