2H-1,4-Benzoxazin-3(4H)-one,4-methyl- → 6-[2-(4-Bromo-2-chloro-phenyl)-acetyl]-4-methyl-4H-benzo[1,4]oxazin-3-one

Participants

Role	Name	HCID	Charge
Reactant	2H-1,4-Benzoxazin-3(4H)-one,4-methyl-	HCID 89032	—
Reactant	Aluminum(III) Chloride	HCID 6451240	—
Reactant	2-(4-Bromo-2-chlorophenyl)acetic acid	HCID 53403617	—
Product	6-[2-(4-Bromo-2-chloro-phenyl)-acetyl]-4-methyl-4H-benzo[1,4]oxazin-3-one	HCID 66697375	—

Reaction Steps

In analogy to Example 1, step 1, (4-bromo-2-chloro-phenyl)-acetic acid was converted to the acid chloride and subsequently reacted with 4-methyl-2H-1,4-benzoxazin-3(4H)-one in the presence of AlCl3 to give the title compound as a light brown solid. MS (m/e, ISP neg. ion)=392.1 [M−H+].

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08268820B2
Source dataset	uspto-grants-2012_09
ORD ID	ord-ba333a086d404fc28cad94cca64d75d8
Source note	uspto-grants-2012_09