Allyl bromide → 4-(2-propen-1-yl)-2H-1,4-Benzoxazin-3(4H)-one

HRID 2386775Notes

Reaction equation

[O:1]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[NH:4][C:3](=[O:11])[CH2:2]1.Br[CH2:13][CH:14]=[CH2:15]>>[CH2:15]([N:4]1[C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[O:1][CH2:2][C:3]1=[O:11])[CH:14]=[CH2:13]

Participants

Reactant 2

HCID 7841Allyl bromide

HCID 727572H-1,4-benzoxazin-3(4H)-one

Product 1

HCID 573460234-(2-propen-1-yl)-2H-1,4-Benzoxazin-3(4H)-one

Procedure

In analogy to Example 64, step 1, 2H-1,4-benzoxazin-3(4H)-one (15 g) was reacted with 3-bromo-propene to give the title compound (17.4 g) as a colorless oil. MS (m/e)=190.3 [M+H+].

Sources & evidence

ORD record: ord-72aef05e118a45f7a908fef675a602cf
Source dataset: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08268820B2

Reaction notes

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