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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2386929Generated: October 31, 2026

1-[3-(4-Nitrophenoxy)propyl]piperidine → 4-[3-(1-Piperidinyl)propoxy]aniline

https://huagongshe.com/reaction/2386929

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[3-(4-Nitrophenoxy)propyl]piperidineHCID 2057928—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product4-[3-(1-Piperidinyl)propoxy]anilineHCID 21974932—

Reaction Steps

1-[3-(4-nitrophenoxy)propyl]piperidine was dissolved in methanol, and the target compound was obtained by catalytic reduction using a palladium charcoal catalyst in a current of hydrogen.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268842B2
Source datasetuspto-grants-2012_09
ORD IDord-0062b87a56054e67835b2e093c39bd33
Source noteuspto-grants-2012_09