2-Amino-4-chloropyrimidine → HCID 68603550, compound

Participants

Reaction Steps

tert-Butyl 2-aminoethyl(methyl)carbamate (337 mg, 1.93 mmol) and 4-chloropyrimidin-2-amine (260 mg, 2.01 mmol) were combined under the conditions described in Example 1D to afford tert-butyl 2-[(2-aminopyrimidin-4-yl)amino]ethyl(methyl)carbamate. MS (M+H)+ m/z 268.3. The intermediate was treated under the conditions of Example 1E to afford the title compound. MS (ESI+) m/z 167.9 (M+H)+.

Provenance & Evidence