HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 1-Chloro-6-(trifluoromethyl)indane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 6-(Trifluoromethyl)-2,3-dihydro-1H-inden-1-OL | HCID 59212663 | — |
| Product | 1-Chloro-6-(trifluoromethyl)indane | HCID 59212653 | 90% |
Reaction Steps
6-(Trifluoromethyl)indan-1-ol (1.52 g, 7.5 mmol) was dissolved in thionyl chloride (15 mL). After being stirred at room temperature for 2 hrs, the solution was concentrated in vacuo to provide the title compound (1.5 g, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268826B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-e7f963864f1143e98eaacb76a9265e05 |
| Source note | uspto-grants-2012_09 |