Phenylboronic Acid → HCID 59423958, compound

HRID 2387681Notes

Reaction equation

Br[C:2]1[CH:3]=[C:4]([CH:32]=[CH:33][CH:34]=1)[CH2:5][O:6][C@H:7]1[CH2:11][CH2:10][N:9]([C:12]([CH3:31])([CH3:30])[CH2:13][CH2:14][C:15]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:16]#[N:17])[CH2:8]1.[C:35]1(B(O)O)[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1>>[C:2]1([C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[CH:34]=[CH:33][CH:32]=[C:4]([CH2:5][O:6][C@H:7]2[CH2:11][CH2:10][N:9]([C:12]([CH3:31])([CH3:30])[CH2:13][CH2:14][C:15]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[C:16]#[N:17])[CH2:8]2)[CH:3]=1

Participants

Reactant 2

HCID 66827Phenylboronic Acid

HCID 59423922HCID 59423922, compound

Product 1

HCID 59423958HCID 59423958, compoundYield 54%

Procedure

The title compound was prepared from the product of example 55 and benzeneboronic acid, using the same method as that described for example 56, as a green gum in 54% yield.

Sources & evidence

ORD record: ord-af8e27d09302466d9870ac18b2a58f43
Source dataset: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08268881B2

Reaction notes

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