反应详情

A mixture of the product from step (i) (40 g) and 5% Pd—C (3 g) in EtOAc were hydrogenated at 3 Bar for 48 h. The mixture was filtered through celite and evaporated under reduced pressure. The residue was purified by column chromatography eluting with 30% EtOAc/iso-hexane to afford the subtitle compound, 23.35 g.

1. filtrationThe mixture was filtered through celite
2. customevaporated under reduced pressure
3. customThe residue was purified by column chromatography
4. washeluting with 30% EtOAc/iso-hexane