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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2387942Generated: November 1, 2026

Trifluoroacetic acid → HCID 59367776, compound

https://huagongshe.com/reaction/2387942

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 67356290HCID 67356290—
SolventDichloromethaneHCID 6344—
ProductHCID 59367776HCID 59367776—

Reaction Conditions

Temperature25 °C

Reaction Steps

3-Pyridin-3-yl-3-(2-pyrrolidin-1-yl-ethoxy)-9-azaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester (0.282 mmol, 1 equiv.) was dissolved in DCM (3 ml). At 0° C., trifluoroacetic acid (1.5 ml) was added, and the mixture was stirred for 2 hours at 25° C. The solvent was concentrated under reduced pressure and the residue was taken up in DCM (2×10 ml) and dried to yield the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08269000B2
Source datasetuspto-grants-2012_09
ORD IDord-25a3f0c666944dac9ac35fa8a6ab29c7
Source noteuspto-grants-2012_09