HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2387942Generated: November 1, 2026
Trifluoroacetic acid → HCID 59367776, compound
https://huagongshe.com/reaction/2387942
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 67356290 | HCID 67356290 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59367776 | HCID 59367776 | — |
Reaction Steps
3-Pyridin-3-yl-3-(2-pyrrolidin-1-yl-ethoxy)-9-azaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester (0.282 mmol, 1 equiv.) was dissolved in DCM (3 ml). At 0° C., trifluoroacetic acid (1.5 ml) was added, and the mixture was stirred for 2 hours at 25° C. The solvent was concentrated under reduced pressure and the residue was taken up in DCM (2×10 ml) and dried to yield the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08269000B2 |
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| Source dataset | uspto-grants-2012_09 |
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| ORD ID | ord-25a3f0c666944dac9ac35fa8a6ab29c7 |
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| Source note | uspto-grants-2012_09 |
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