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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2388074Generated: October 31, 2026

2-Chloro-4-(trifluoromethyl)benzenesulfonyl chloride → HCID 24852701, compound

https://huagongshe.com/reaction/2388074

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-(trifluoromethyl)benzenesulfonyl chlorideHCID 2736675—
Reactant5-Chloro-6-(quinolin-3-yloxy)pyridin-3-amineHCID 68790798—
ProductHCID 24852701HCID 24852701—

Reaction Steps

The title compound was prepared by reacting 5-chloro-6-(quinolin-3-yloxy)pyridin-3-amine (obtained as per procedure described in preparation 1) and 2-chloro-4-(trifluoromethyl)benzene-1-sulfonyl chloride. 1H NMR (DMSO-d6) δ: 7.60 (s, 1H), 7.72-7.77 (m, 3H), 7.90 (s, 2H), 8.00 (s, 1H), 8.13-8.20 (m, 3H), 8.75 (s, 1H), 11.21 (s, 1H); MS (ES): 513.99 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08269010B2
Source datasetuspto-grants-2012_09
ORD IDord-1f3d57e264754b6f9db350c26d4c7886
Source noteuspto-grants-2012_09