反应详情

温度

120 °C

5-Chloro-6-(quinolin-3-yloxy)-pyridin-3-yl amine (1 mmol) (obtained as per procedure described in preparation 1) was dissolved in toluene under heating. To the clear solution was added succinic anhydride (1 mmol) and refluxed at 120° C. for 6 hours. The solvent the evaporated and the crude obtained was purified by column chromatography to provide the title compound.

1. temperatureunder heating
2. customThe solvent the evaporated
3. customthe crude obtained
4. customwas purified by column chromatography