Methyl iodide → HCID 66750436, compound

HRID 2388336Notes

Reaction equation

HRID 2388336 reaction equation
[O:1]1[C:5]2([CH2:10][CH2:9][C:8]([C:11]3[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=3)=[CH:7][CH2:6]2)[O:4][CH2:3][CH2:2]1.[CH3:17][I:18]>>[I-:18].[O:1]1[C:5]2([CH2:10][CH2:9][C:8]([C:11]3[CH:12]=[CH:13][N+:14]([CH3:17])=[CH:15][CH:16]=3)=[CH:7][CH2:6]2)[O:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 137720544-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)pyridine

Product 1

HCID 66750436HCID 66750436, compound

Procedure

4-(1,4-Dioxa-spiro[4.5]dec-7-en-8-yl)-pyridine (as prepared in the previous step, 1.5 g, 6.91 mmol) in MeI (˜10 mL) was heated to reflux until the precipitate was completely dissolved. The reaction was cooled and filtered to collect the brown solid as the title compound.

Workup

  1. temperaturewas heated
  2. temperatureto reflux until the precipitate
  3. dissolutionwas completely dissolved
  4. temperatureThe reaction was cooled
  5. filtrationfiltered
  6. customto collect the brown solid as the title compound

Sources & evidence

ORD record
ord-41bcb0a6e77b4ac2a44f5aaf1c81b085
Source dataset
uspto-grants-2012_09
Patent number
US08269015B2

Reaction notes

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