Trifluoroacetic acid → HCID 57948664, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of (S)-tert-butyl 2-((1-(4-methoxy-2,6-dimethylphenylsulfonyl)-pyrrolidin-2-yl)methoxy)acetate (1 eq.) in dichloromethane (10 ml/mmol) was added trifluoroacetic acid (2 ml/mmol) at 0° C. and the resulting reaction mixture was stirred at 25° C. for 2 h. The solvent was evaporated off and it was dried under vacuum to remove traces of trifluoroacetic acid. The crude product was used directly for the next step. Yield: quantitative.

Provenance & Evidence