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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2388683Generated: November 1, 2026

1-Methylhomopiperazine → 2-((4-Methyl-1,4-diazepan-1-yl)methyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine

https://huagongshe.com/reaction/2388683

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylhomopiperazineHCID 228349—
Reactant2-(Pyrrolidin-1-ylmethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridineHCID 17796611—
Product2-((4-Methyl-1,4-diazepan-1-yl)methyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridineHCID 57948682—

Reaction Steps

The preparation of this amine was carried out in analogy to that described for 2-(pyrrolidin-1-ylmethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine (TP1 1) employing 1-methyl-1,4-diazepane in step-8.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268814B2
Source datasetuspto-grants-2012_09
ORD IDord-6225aabe4cd3497dafab1e3a207f68b6
Source noteuspto-grants-2012_09