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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2388711Generated: November 3, 2026

Trifluoroacetic acid → HCID 28293479, compound

https://huagongshe.com/reaction/2388711

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 68644070HCID 68644070—
SolventDichloromethaneHCID 6344—
ProductHCID 28293479HCID 28293479—

Reaction Steps

To a cooled (0° C.) solution of tert-butyl 2-(piperidin-1-ylmethyl)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate (0.534 mmol) in dichloromethane (3 ml) was added trifluoroacetic acid (1 ml) and reaction mixture was stirred at room temperature for 2 h. Solvent was evaporated under reduced pressure and residue was azeotroped twice with dichloromethane and used in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268814B2
Source datasetuspto-grants-2012_09
ORD IDord-54b9509cbd18448f9b95f25ec90d1251
Source noteuspto-grants-2012_09