HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 28293479, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68644070 | HCID 68644070 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 28293479 | HCID 28293479 | — |
Reaction Steps
To a cooled (0° C.) solution of tert-butyl 2-(piperidin-1-ylmethyl)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate (0.534 mmol) in dichloromethane (3 ml) was added trifluoroacetic acid (1 ml) and reaction mixture was stirred at room temperature for 2 h. Solvent was evaporated under reduced pressure and residue was azeotroped twice with dichloromethane and used in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268814B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-54b9509cbd18448f9b95f25ec90d1251 |
| Source note | uspto-grants-2012_09 |