HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 12273165, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1-(2-Chloro-5-nitrophenyl)ethan-1-one | HCID 89996 | — |
| Product | HCID 12273165 | HCID 12273165 | 96% |
Reaction Steps
Procedure A was performed with 2′-chloro-5′-nitro-acetophenone (4.0 g, 20 mmol) and bromine (1.13 ml, 22 mmol). The crude product was purified by flash column chromatography on silica gel eluting with EtOAc:hexanes (0:1 to 1:4) to afford the desired 2-bromo-2′chloro-5′-nitroacetophenone (5.4 g, 19.2 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273743B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-0d43354f6a2f4af8ad7ef9c622e41b71 |
| Source note | uspto-grants-2012_09 |