HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 42614143, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Boc-3-amino-1,2,3,4-tetrahydroquinoline | HCID 4460996 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 42614143 | HCID 42614143 | — |
Reaction Steps
To a stirred room temperature solution of tert-butyl 1,2,3,4-tetrahydroquinolin-3-ylcarbamate (1.0 g) in ethyl acetate (20 mL) was added 4 M HCl in dioxane (10 mL). After 6 hours the mixture was evaporated to dryness to obtain 1,2,3,4-tetrahydroquinolin-3-amine bis HCl salt as a cream colored solid (925 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273754B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-f5d16909f23f49f2994403194b6e4c0c |
| Source note | uspto-grants-2012_09 |