HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride → tert-butyl 1-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-4-ylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | tert-butyl 2,3,4,5-tetrahydro-1H-benzo[b]azepin-4-ylcarbamate | HCID 59400102 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | tert-butyl 1-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-4-ylcarbamate | HCID 59400071 | — |
Reaction Steps
To a stirred room temperature solution of tert-butyl 2,3,4,5-tetrahydro-1H-benzo[b]azepin-4-ylcarbamate (39.3 mg, 0.15 mmol) in 1,2-dichloroethane (4 mL) was added benzenesulfonyl chloride (26.4 mg, 0.15 mmol). After 16 hours the mixture was evaporated to dryness to yield tert-butyl 1-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-4-ylcarbamate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273754B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-14aa3b18ffab4ed08134836ab992e3a8 |
| Source note | uspto-grants-2012_09 |