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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2389582Generated: October 25, 2026

5-Bromo-2-ethoxybenzaldehyde → 4'-Ethoxy-3'-formyl-biphenyl-4-carbonitrile

https://huagongshe.com/reaction/2389582

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-ethoxybenzaldehydeHCID 144901—
Reactant4-Cyanophenylboronic acidHCID 2734326—
Product4'-Ethoxy-3'-formyl-biphenyl-4-carbonitrileHCID 22049663—

Reaction Steps

4-cyanophenylboronic acid (500 mg, 3.40 mmol) is coupled to 5-bromo-2-ethoxybenzaldehyde (780 mg, 3.40 mmol) using Method A to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273747B2
Source datasetuspto-grants-2012_09
ORD IDord-e517a6639ae649dca56e6e5b6308caad
Source noteuspto-grants-2012_09