1-Phenylpiperazine → HCID 22569959, compound

HRID 23896Notes

Reaction equation

HRID 23896 reaction equation
[CH3:1][O:2][C:3]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][O:10][C:11]1[CH:12]=[CH:13][C:14]2[N:18]=[C:17]([C:19]3[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=3)[N:16]([CH2:27][CH2:28][CH:29]=O)[C:15]=2[CH:31]=1)=[O:4].[C:32]1([N:38]2[CH2:43][CH2:42][NH:41][CH2:40][CH2:39]2)[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[CH3:1][O:2][C:3]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][O:10][C:11]1[CH:12]=[CH:13][C:14]2[N:18]=[C:17]([C:19]3[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=3)[N:16]([CH2:27][CH2:28][CH2:29][N:41]3[CH2:42][CH2:43][N:38]([C:32]4[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=4)[CH2:39][CH2:40]3)[C:15]=2[CH:31]=1)=[O:4]

Participants

3

Reactant 2

HCID 70961-PhenylpiperazineHCID 225699366-[(5-(Methoxycarbonyl)pentyl)oxy]-2-(4-methoxy-phenyl)-1-(3-oxo-propyl)-benzimidazole

Product 1

HCID 22569959HCID 22569959, compound

Procedure

6-[(5-(Methoxycarbonyl)pentyl)oxy]-2-(4-methoxy-phenyl)-1-(3-oxo-propyl)-benzimidazole is reacted with N-phenyl-piperazine according to general operating instructions 8. 6-[(5-(Methoxycarbonyl)pentyl)oxy]-2-(4-methoxy-phenyl)-1-[3-(4-phenyl-piperazin-1-yl)-propyl]-benzimidazole is obtained as a yellow oil.

Sources & evidence

ORD record
ord-78b782427791440688a99088a097f92a
Source dataset
uspto-grants-2005_02
Patent number
US06855714B2

Reaction notes

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