HRID23896

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7096

Phenylpiperazine

C10H14N2

结构：COC(=O)CCCCCOc1ccc2nc(-c3ccc(OC)cc3)n(CCC=O)c2c1

HCID22569936

未命名化合物

PRODUCTS

生成物

结构：COC(=O)CCCCCOc1ccc2nc(-c3ccc(OC)cc3)n(CCCN3CCN(c4ccccc4)CC3)c2c1

HCID22569959

未命名化合物

PROCEDURE

实验过程

6-[(5-(Methoxycarbonyl)pentyl)oxy]-2-(4-methoxy-phenyl)-1-(3-oxo-propyl)-benzimidazole is reacted with N-phenyl-piperazine according to general operating instructions 8. 6-[(5-(Methoxycarbonyl)pentyl)oxy]-2-(4-methoxy-phenyl)-1-[3-(4-phenyl-piperazin-1-yl)-propyl]-benzimidazole is obtained as a yellow oil.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-78b782427791440688a99088a097f92a
来源数据集: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06855714B2
来源说明: uspto-grants-2005_02

反应 SMILES

[CH3:1][O:2][C:3]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][O:10][C:11]1[CH:12]=[CH:13][C:14]2[N:18]=[C:17]([C:19]3[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=3)[N:16]([CH2:27][CH2:28][CH:29]=O)[C:15]=2[CH:31]=1)=[O:4].[C:32]1([N:38]2[CH2:43][CH2:42][NH:41][CH2:40][CH2:39]2)[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[CH3:1][O:2][C:3]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][O:10][C:11]1[CH:12]=[CH:13][C:14]2[N:18]=[C:17]([C:19]3[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=3)[N:16]([CH2:27][CH2:28][CH2:29][N:41]3[CH2:42][CH2:43][N:38]([C:32]4[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=4)[CH2:39][CH2:40]3)[C:15]=2[CH:31]=1)=[O:4]