HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl methyl ether → HCID 86618971, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl methyl ether | HCID 15413 | — |
| Reactant | HCID 59683577 | HCID 59683577 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86618971 | HCID 86618971 | — |
Reaction Steps
tert-Butyl carbamate 97 (250 mg, 0.34 mmol) is deprotected using Method F. The isolated salt is then dissolved in the minimum amount of DCM and added dropwise to cold (0° C.) TBME (25 mL). The resultant white precipitate is isolated by filtration and dried to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273747B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-0b284c4001844c8da021aad648006d24 |
| Source note | uspto-grants-2012_09 |