反应详情

tert-Butyl carbamate 217 (100 mg, 0.14 mmol) is deprotected using Method F. The isolated salt is then dissolved in the minimum amount of DCM and added dropwise to cold (0° C.) TBME (25 mL). The resultant pale yellow precipitate is isolated by filtration, washed with TBME (10 mL) and diethyl ether (10 mL) and dried to afford the title compound.

1. customThe resultant pale yellow precipitate is isolated by filtration
2. washwashed with TBME (10 mL) and diethyl ether (10 mL)
3. customdried