3-Chloro-4-fluoro-1-benzothiophene-2-carbonyl chloride → (4-{(3-Chloro-4-fluoro-benzo[b]thiophene-2-carbonyl)-[2-methoxy-5-(6-methyl-pyridin-3-yl)-benzyl]-amino}-cyclohexyl)-methyl-carbamic acid tert-butyl ester

Participants

Role	Name	HCID	Charge
Reactant	3-Chloro-4-fluoro-1-benzothiophene-2-carbonyl chloride	HCID 12594645	—
Reactant	tert-Butyl {4-[2-methoxy-5-(6-methyl-pyridin-3-yl)-benzylamino]-cyclohexyl}-methyl-carbamate	HCID 59683457	—
Product	(4-{(3-Chloro-4-fluoro-benzo[b]thiophene-2-carbonyl)-[2-methoxy-5-(6-methyl-pyridin-3-yl)-benzyl]-amino}-cyclohexyl)-methyl-carbamic acid tert-butyl ester	HCID 59766920	—

The title compound was prepared from amine (281) (200 mg, 0.45 mmol) and acid chloride 6 (170 mg, 6.8 mmol) following Method D.