HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 68710392, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 59312893 | HCID 59312893 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68710392 | HCID 68710392 | — |
Reaction Steps
6-[(2-Aminoethyl)thio]-3-nitropyridine-2-amine trifluoroacetate (Example 46A) is prepared in analogy to Example 40A from tert-butyl {2-[(6-amino-5-nitropyridin-2-yl)thio]ethyl}carbamate (Example 43A) (380 mg, 1.2 mmol) and trifluoroacetic acid (1.9 ml, 24 mmol) in dichloromethane (20 ml). 400 mg of the product are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273752B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-10387ba169e24ca5ab28c2cc5a18e993 |
| Source note | uspto-grants-2012_09 |