Furo[3,2-c]pyrazolo[1,5-a]pyridin-1-ylacetonitrile → 2-Furo[3,2-c]pyrazolo[1,5-a]pyridin-1-ylethanamine

Participants

Reaction Steps

Furo[3,2-c]pyrazolo[1,5-a]pyridin-1-ylacetonitrile (55.0 mg, 0.279 mmol) and Raney cobalt (500 mg) were suspended in 2M ammonia/methanol solution (10 mL), and the suspension was stirred at room temperature for 3 hr under a hydrogen atmosphere. The catalyst was filtered through celite, and the filtrate was concentrated under reduced pressure to give the title compound (55.5 mg, yield 99%).

Provenance & Evidence