HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 53308978, compound → 2-(2-Ethyl-8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridin-1-yl)ethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 53308978 | HCID 53308978 | — |
| Catalyst | Cobalt | HCID 104730 | — |
| Solvent | Ammonia methanol | HCID 21705897 | — |
| Product | 2-(2-Ethyl-8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridin-1-yl)ethanamine | HCID 53308983 | 98.3% |
Reaction Steps
(2-Ethyl-8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridin-1-yl)acetonitrile (120 mg, 0.528 mmol) and Raney cobalt (1.2 g) were suspended in 2M ammonia/methanol solution (25 mL), and the suspension was stirred at room temperature for 12 hr under a hydrogen atmosphere. The catalyst was filtered through celite, and the filtrate was concentrated under reduced pressure to give the title compound (120 mg, yield 98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273761B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-51c3d1c54d1247e0bccd10ed11ef149e |
| Source note | uspto-grants-2012_09 |