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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2389887Generated: November 1, 2026

HCID 53308978, compound → 2-(2-Ethyl-8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridin-1-yl)ethanamine

https://huagongshe.com/reaction/2389887

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 53308978HCID 53308978—
CatalystCobaltHCID 104730—
SolventAmmonia methanolHCID 21705897—
Product2-(2-Ethyl-8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridin-1-yl)ethanamineHCID 5330898398.3%

Reaction Steps

(2-Ethyl-8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridin-1-yl)acetonitrile (120 mg, 0.528 mmol) and Raney cobalt (1.2 g) were suspended in 2M ammonia/methanol solution (25 mL), and the suspension was stirred at room temperature for 12 hr under a hydrogen atmosphere. The catalyst was filtered through celite, and the filtrate was concentrated under reduced pressure to give the title compound (120 mg, yield 98%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273761B2
Source datasetuspto-grants-2012_09
ORD IDord-51c3d1c54d1247e0bccd10ed11ef149e
Source noteuspto-grants-2012_09